2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid
≥95%
- Product Code: 195549
CAS:
849928-23-0
| Molecular Weight: | 506.59 g./mol | Molecular Formula: | C₂₉H₃₄N₂O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD07779072 | |
| Melting Point: | Boiling Point: | 674.2°C at 760 mmHg | |
| Density: | 1.31g/cm3 | Storage Condition: | 2-8°C, dry seal |
Product Description:
Used primarily in peptide synthesis as a protected spirocyclic diamine building block. Its structure allows for selective deprotection and coupling, making it valuable in the preparation of complex peptides and peptidomimetics. The Fmoc group enables solid-phase synthesis by providing orthogonal protection, while the tert-butoxycarbonyl (Boc) group stabilizes the second amine during chain elongation. Commonly applied in medicinal chemistry for developing protease inhibitors and bioactive molecules requiring constrained ring systems. Its spiro architecture imparts conformational rigidity, enhancing target selectivity and metabolic stability in drug design.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | £228.86 |
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| 1g | 10-20 days | £886.98 |
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| 100mg | 10-20 days | £101.92 |
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2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid
Used primarily in peptide synthesis as a protected spirocyclic diamine building block. Its structure allows for selective deprotection and coupling, making it valuable in the preparation of complex peptides and peptidomimetics. The Fmoc group enables solid-phase synthesis by providing orthogonal protection, while the tert-butoxycarbonyl (Boc) group stabilizes the second amine during chain elongation. Commonly applied in medicinal chemistry for developing protease inhibitors and bioactive molecules requiring constrained ring systems. Its spiro architecture imparts conformational rigidity, enhancing target selectivity and metabolic stability in drug design.
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