(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate
≥95%
- Product Code: 195556
CAS:
340187-12-4
Molecular Weight: | 346.22 g./mol | Molecular Formula: | C₁₇H₁₆BrNO₂ |
---|---|---|---|
EC Number: | MDL Number: | MFCD00797866 | |
Melting Point: | Boiling Point: | 491.9°C at 760 mmHg | |
Density: | Storage Condition: | 2-8°C, dry seal |
Product Description:
Used primarily as a key intermediate in the synthesis of pharmaceuticals and bioactive molecules, especially in the development of protected amines for peptide and heterocyclic compound synthesis. The (9H-fluoren-9-yl)methyl (Fmoc) group acts as a protecting group for amines, allowing selective reaction at other functional sites during multi-step syntheses. Its stability under acidic conditions and easy removal under mild basic conditions (e.g., with piperidine) makes it highly valuable in solid-phase peptide synthesis. The bromoethyl moiety provides a reactive handle for further alkylation or cyclization reactions, enabling the construction of complex nitrogen-containing structures such as amino acids, drug candidates, and functionalized polymers. Commonly employed in medicinal chemistry for the preparation of targeted therapeutics, including kinase inhibitors and receptor modulators.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
---|---|---|---|
5g | 10-20 days | ฿1,730.00 |
+
-
|
10g | 10-20 days | ฿2,770.00 |
+
-
|
25g | 10-20 days | ฿5,540.00 |
+
-
|
(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate
Used primarily as a key intermediate in the synthesis of pharmaceuticals and bioactive molecules, especially in the development of protected amines for peptide and heterocyclic compound synthesis. The (9H-fluoren-9-yl)methyl (Fmoc) group acts as a protecting group for amines, allowing selective reaction at other functional sites during multi-step syntheses. Its stability under acidic conditions and easy removal under mild basic conditions (e.g., with piperidine) makes it highly valuable in solid-phase peptide synthesis. The bromoethyl moiety provides a reactive handle for further alkylation or cyclization reactions, enabling the construction of complex nitrogen-containing structures such as amino acids, drug candidates, and functionalized polymers. Commonly employed in medicinal chemistry for the preparation of targeted therapeutics, including kinase inhibitors and receptor modulators.
Mechanism | - |
Appearance | - |
Longevity | - |
Strength | - |
Storage | - |
Shelf Life | - |
Allergen(s) | - |
Dosage (Range) | - |
Recommended Dosage | - |
Dosage (Per Day) | - |
Recommended Dosage (Per Day) | - |
Mix Method | - |
Heat Resistance | - |
Stable in pH range | - |
Solubility | - |
Product Types | - |
INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :