(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate

≥95%

  • Product Code: 195556
  CAS:    340187-12-4
Molecular Weight: 346.22 g./mol Molecular Formula: C₁₇H₁₆BrNO₂
EC Number: MDL Number: MFCD00797866
Melting Point: Boiling Point: 491.9°C at 760 mmHg
Density: Storage Condition: 2-8°C, dry seal
Product Description: Used primarily as a key intermediate in the synthesis of pharmaceuticals and bioactive molecules, especially in the development of protected amines for peptide and heterocyclic compound synthesis. The (9H-fluoren-9-yl)methyl (Fmoc) group acts as a protecting group for amines, allowing selective reaction at other functional sites during multi-step syntheses. Its stability under acidic conditions and easy removal under mild basic conditions (e.g., with piperidine) makes it highly valuable in solid-phase peptide synthesis. The bromoethyl moiety provides a reactive handle for further alkylation or cyclization reactions, enabling the construction of complex nitrogen-containing structures such as amino acids, drug candidates, and functionalized polymers. Commonly employed in medicinal chemistry for the preparation of targeted therapeutics, including kinase inhibitors and receptor modulators.
Sizes / Availability / Pricing:
Size Availability Price Quantity
5g 10-20 days ฿1,730.00
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10g 10-20 days ฿2,770.00
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25g 10-20 days ฿5,540.00
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(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate
Used primarily as a key intermediate in the synthesis of pharmaceuticals and bioactive molecules, especially in the development of protected amines for peptide and heterocyclic compound synthesis. The (9H-fluoren-9-yl)methyl (Fmoc) group acts as a protecting group for amines, allowing selective reaction at other functional sites during multi-step syntheses. Its stability under acidic conditions and easy removal under mild basic conditions (e.g., with piperidine) makes it highly valuable in solid-phase peptide synthesis. The bromoethyl moiety provides a reactive handle for further alkylation or cyclization reactions, enabling the construction of complex nitrogen-containing structures such as amino acids, drug candidates, and functionalized polymers. Commonly employed in medicinal chemistry for the preparation of targeted therapeutics, including kinase inhibitors and receptor modulators.
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