6-(difluoromethoxy)-2-[(3,4-dimethoxy-1-oxidopyridin-1-ium-2-yl)methylsulfonyl]-1H-benzimidazole

98%

  • Product Code: 195984
  CAS:    953787-55-8
Molecular Weight: 415.369 g./mol Molecular Formula: C₁₆H₁₅F₂N₃O₆S
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, dryness, shading
Product Description: Used primarily as an intermediate in the synthesis of proton pump inhibitors (PPIs), this compound plays a key role in the development of medications that reduce gastric acid production. It is especially valuable in the preparation of anti-ulcer drugs, targeting conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Due to its sulfonyl and benzimidazole functional groups, it enables selective inhibition of the H+/K+-ATPase enzyme system in the parietal cells of the stomach, which is critical for acid secretion. Its difluoromethoxy and dimethoxy-oxidopyridinium moieties enhance metabolic stability and bioavailability in final drug formulations. Commonly used in pharmaceutical research and development, it supports the production of long-acting, potent acid-suppressive agents.
Sizes / Availability / Pricing:
Size Availability Price Quantity
20mg 10-20 days ฿2,808.00
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50mg 10-20 days ฿3,888.00
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100mg 10-20 days ฿5,670.00
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250mg 10-20 days ฿9,450.00
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1g 10-20 days ฿24,732.00
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bulk 10-20 days ฿0.00
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6-(difluoromethoxy)-2-[(3,4-dimethoxy-1-oxidopyridin-1-ium-2-yl)methylsulfonyl]-1H-benzimidazole
Used primarily as an intermediate in the synthesis of proton pump inhibitors (PPIs), this compound plays a key role in the development of medications that reduce gastric acid production. It is especially valuable in the preparation of anti-ulcer drugs, targeting conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Due to its sulfonyl and benzimidazole functional groups, it enables selective inhibition of the H+/K+-ATPase enzyme system in the parietal cells of the stomach, which is critical for acid secretion. Its difluoromethoxy and dimethoxy-oxidopyridinium moieties enhance metabolic stability and bioavailability in final drug formulations. Commonly used in pharmaceutical research and development, it supports the production of long-acting, potent acid-suppressive agents.
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