6-(1-Hydroxy-1,3-dihydro-benzo[c][1,2]oxaborol-5-yloxy)-2-(2-methoxy-ethoxy)-nicotinonitrile

≥95%

  • Product Code: 196171
  CAS:    1187187-28-5
Molecular Weight: 326.11 g./mol Molecular Formula: C₁₆H₁₅BN₂O₅
EC Number: MDL Number:
Melting Point: Boiling Point: 508.0±60.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted) Storage Condition: Room temperature
Product Description: Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting BTK (Bruton's tyrosine kinase) for the treatment of autoimmune diseases and certain cancers. Its boron-containing structure enhances binding selectivity and potency in drug candidates. Also explored in prodrug formulations due to improved solubility and metabolic stability. Commonly applied in structure-activity relationship (SAR) studies to optimize pharmacokinetic properties in oncology and inflammation pipelines.
Sizes / Availability / Pricing:
Size Availability Price Quantity
5mg 10-20 days ฿26,130.00
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6-(1-Hydroxy-1,3-dihydro-benzo[c][1,2]oxaborol-5-yloxy)-2-(2-methoxy-ethoxy)-nicotinonitrile
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting BTK (Bruton's tyrosine kinase) for the treatment of autoimmune diseases and certain cancers. Its boron-containing structure enhances binding selectivity and potency in drug candidates. Also explored in prodrug formulations due to improved solubility and metabolic stability. Commonly applied in structure-activity relationship (SAR) studies to optimize pharmacokinetic properties in oncology and inflammation pipelines.
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