1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylcyclobutanecarboxylicacid

96%

  • Product Code: 197570
  CAS:    1936161-54-4
Molecular Weight: 365.42 g./mol Molecular Formula: C₂₂H₂₃NO₄
EC Number: MDL Number: MFCD30235040
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature
Product Description: Widely used in peptide synthesis as a protected amino acid building block. The Fmoc group provides temporary protection for the amine functionality, allowing selective reaction at the carboxylic acid site. This compound is particularly useful for incorporating sterically hindered, non-natural amino acid residues into peptides, enhancing stability and modulating biological activity. Its cyclobutane backbone with geminal dimethyl groups introduces conformational restraint, which can improve metabolic resistance and binding selectivity in peptidomimetic drug design. Commonly employed in solid-phase synthesis due to its compatibility with Fmoc deprotection conditions (piperidine treatment), enabling stepwise assembly of complex peptides.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿14,370.00
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250mg 10-20 days ฿22,950.00
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-
1g 10-20 days ฿57,260.00
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1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylcyclobutanecarboxylicacid
Widely used in peptide synthesis as a protected amino acid building block. The Fmoc group provides temporary protection for the amine functionality, allowing selective reaction at the carboxylic acid site. This compound is particularly useful for incorporating sterically hindered, non-natural amino acid residues into peptides, enhancing stability and modulating biological activity. Its cyclobutane backbone with geminal dimethyl groups introduces conformational restraint, which can improve metabolic resistance and binding selectivity in peptidomimetic drug design. Commonly employed in solid-phase synthesis due to its compatibility with Fmoc deprotection conditions (piperidine treatment), enabling stepwise assembly of complex peptides.
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