IDO-IN-1
10mM in DMSO
- Product Code: 198961
CAS:
914638-30-5
| Molecular Weight: | 316.09 g./mol | Molecular Formula: | C₉H₇BrFN₅O₂ |
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| Density: | Storage Condition: | -20°C |
Product Description:
IDO-IN-1 is a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme involved in immune regulation. Its primary application lies in cancer immunotherapy, where it helps reverse the immunosuppressive tumor microenvironment. By blocking IDO1 activity, IDO-IN-1 prevents the breakdown of tryptophan, thereby restoring T-cell function and enhancing anti-tumor immune responses. It is widely used in research settings to study immune checkpoint pathways and to develop combination therapies with other immunotherapeutic agents such as PD-1/PD-L1 inhibitors. Additionally, IDO-IN-1 has been explored in inflammatory and autoimmune disease models due to the role of IDO1 in modulating immune tolerance.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿1,860.00 |
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IDO-IN-1
IDO-IN-1 is a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme involved in immune regulation. Its primary application lies in cancer immunotherapy, where it helps reverse the immunosuppressive tumor microenvironment. By blocking IDO1 activity, IDO-IN-1 prevents the breakdown of tryptophan, thereby restoring T-cell function and enhancing anti-tumor immune responses. It is widely used in research settings to study immune checkpoint pathways and to develop combination therapies with other immunotherapeutic agents such as PD-1/PD-L1 inhibitors. Additionally, IDO-IN-1 has been explored in inflammatory and autoimmune disease models due to the role of IDO1 in modulating immune tolerance.
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