IKK-16
10mM in DMSO
- Product Code: 198974
CAS:
873225-46-8
| Molecular Weight: | 483.63 g./mol | Molecular Formula: | C₂₈H₂₉N₅OS |
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| Density: | Storage Condition: | -20°C |
Product Description:
IKK-16 is a selective inhibitor of IκB kinase (IKK), particularly targeting the IKKβ subunit. It is widely used in research to suppress NF-κB signaling, a key pathway involved in inflammation, immune response, and cell survival. Due to its ability to block NF-κB activation, IKK-16 has been studied in models of inflammatory diseases such as arthritis, sepsis, and inflammatory bowel disease. It also shows potential in cancer research, where constitutive NF-κB activity supports tumor growth and resistance to therapy. By inhibiting this pathway, IKK-16 can enhance the effectiveness of chemotherapeutic agents and promote apoptosis in certain cancer cell types. Its use is primarily limited to preclinical studies, serving as a tool compound to explore the therapeutic benefits of IKK and NF-κB inhibition.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿7,270.00 |
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IKK-16
IKK-16 is a selective inhibitor of IκB kinase (IKK), particularly targeting the IKKβ subunit. It is widely used in research to suppress NF-κB signaling, a key pathway involved in inflammation, immune response, and cell survival. Due to its ability to block NF-κB activation, IKK-16 has been studied in models of inflammatory diseases such as arthritis, sepsis, and inflammatory bowel disease. It also shows potential in cancer research, where constitutive NF-κB activity supports tumor growth and resistance to therapy. By inhibiting this pathway, IKK-16 can enhance the effectiveness of chemotherapeutic agents and promote apoptosis in certain cancer cell types. Its use is primarily limited to preclinical studies, serving as a tool compound to explore the therapeutic benefits of IKK and NF-κB inhibition.
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