IWP-2
2mM in DMSO
- Product Code: 199070
CAS:
686770-61-6
| Molecular Weight: | 466.59 g./mol | Molecular Formula: | C₂₂H₁₈N₄O₂S₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD04457599 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
IWP-2 is widely used in stem cell research and developmental biology due to its ability to selectively inhibit the Wnt signaling pathway. By targeting the porcupine enzyme, IWP-2 prevents the palmitoylation and secretion of Wnt proteins, effectively suppressing autocrine and paracrine Wnt signaling. This property makes it valuable for controlling differentiation in pluripotent stem cells, particularly in directing cell fate toward specific lineages such as cardiomyocytes or endodermal cells. It is also employed in cancer research, where aberrant Wnt signaling contributes to tumor growth, allowing scientists to study pathway involvement in tumor progression and screen potential therapeutic strategies. Additionally, IWP-2 is used in organoid cultures to modulate tissue development and maintain structural organization.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | $98.04 |
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IWP-2
IWP-2 is widely used in stem cell research and developmental biology due to its ability to selectively inhibit the Wnt signaling pathway. By targeting the porcupine enzyme, IWP-2 prevents the palmitoylation and secretion of Wnt proteins, effectively suppressing autocrine and paracrine Wnt signaling. This property makes it valuable for controlling differentiation in pluripotent stem cells, particularly in directing cell fate toward specific lineages such as cardiomyocytes or endodermal cells. It is also employed in cancer research, where aberrant Wnt signaling contributes to tumor growth, allowing scientists to study pathway involvement in tumor progression and screen potential therapeutic strategies. Additionally, IWP-2 is used in organoid cultures to modulate tissue development and maintain structural organization.
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