Ispinesib (SB-715992)
10mM in DMSO
- Product Code: 199094
CAS:
336113-53-2
| Molecular Weight: | 517.0599999999999 g./mol | Molecular Formula: | C₃₀H₃₃ClN₄O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22628831 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used in cancer research, particularly as a potent inhibitor of kinesin spindle protein (KSP), which plays a critical role in mitosis. By inhibiting KSP, it blocks the formation of the mitotic spindle, leading to cell cycle arrest and apoptosis in rapidly dividing tumor cells. It has been investigated in preclinical and clinical studies for the treatment of various solid tumors and hematologic malignancies. Its mechanism avoids neurotoxicity commonly seen with microtubule-targeting agents, making it a promising candidate in targeted chemotherapy.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿8,600.00 |
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Ispinesib (SB-715992)
Used in cancer research, particularly as a potent inhibitor of kinesin spindle protein (KSP), which plays a critical role in mitosis. By inhibiting KSP, it blocks the formation of the mitotic spindle, leading to cell cycle arrest and apoptosis in rapidly dividing tumor cells. It has been investigated in preclinical and clinical studies for the treatment of various solid tumors and hematologic malignancies. Its mechanism avoids neurotoxicity commonly seen with microtubule-targeting agents, making it a promising candidate in targeted chemotherapy.
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