6-Iodoindolin-2-one
97%
- Product Code: 200583
CAS:
919103-45-0
Molecular Weight: | 259.04 g./mol | Molecular Formula: | C₈H₆INO |
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EC Number: | MDL Number: | MFCD09835633 | |
Melting Point: | Boiling Point: | 365 °C at 760 mmHg | |
Density: | Storage Condition: | Room temperature, away from light, dry, sealed |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to the reactivity of the iodine moiety, enabling cross-coupling reactions such as Suzuki or Heck reactions to introduce diverse aromatic or heteroaromatic groups. Its indolinone core is commonly found in bioactive molecules, making it valuable in drug discovery programs targeting tyrosine kinase pathways. Also explored in the preparation of fluorescent probes and labeled compounds for biochemical assays due to the heavy atom effect of iodine, which can influence photophysical properties.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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100mg | 10-20 days | ฿1,780.00 |
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250mg | 10-20 days | ฿2,690.00 |
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5g | 10-20 days | ฿31,190.00 |
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1g | 10-20 days | ฿7,840.00 |
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6-Iodoindolin-2-one
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to the reactivity of the iodine moiety, enabling cross-coupling reactions such as Suzuki or Heck reactions to introduce diverse aromatic or heteroaromatic groups. Its indolinone core is commonly found in bioactive molecules, making it valuable in drug discovery programs targeting tyrosine kinase pathways. Also explored in the preparation of fluorescent probes and labeled compounds for biochemical assays due to the heavy atom effect of iodine, which can influence photophysical properties.
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