Imidazo[1,2-a]pyrimidine
97%
- Product Code: 200660
CAS:
274-95-3
| Molecular Weight: | 119.12 g./mol | Molecular Formula: | C₆H₅N₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD06245377 | |
| Melting Point: | 127-129 °C | Boiling Point: | |
| Density: | Storage Condition: | Room temperature |
Product Description:
Imidazo[1,2-a]pyrimidine is widely used in pharmaceutical development due to its structural similarity to purine bases, making it a key scaffold in drug design. It exhibits significant biological activity, particularly in the development of anxiolytic and sedative agents. Derivatives of this compound act as positive allosteric modulators of GABAA receptors, enhancing inhibitory neurotransmission in the central nervous system.
It is also explored in antimicrobial and antiviral research, showing promise against certain RNA viruses. Additionally, imidazo[1,2-a]pyrimidine derivatives are investigated for anticancer properties, especially as kinase inhibitors that interfere with tumor cell proliferation. Its versatility in forming stable heterocyclic compounds supports its use in medicinal chemistry and the synthesis of bioactive molecules.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 1g | 10-20 days | $57.23 |
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| 5g | 10-20 days | $191.84 |
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| 10g | 10-20 days | $381.56 |
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| 25g | 10-20 days | $953.89 |
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| 100g | 10-20 days | $3,314.24 |
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Imidazo[1,2-a]pyrimidine
Imidazo[1,2-a]pyrimidine is widely used in pharmaceutical development due to its structural similarity to purine bases, making it a key scaffold in drug design. It exhibits significant biological activity, particularly in the development of anxiolytic and sedative agents. Derivatives of this compound act as positive allosteric modulators of GABAA receptors, enhancing inhibitory neurotransmission in the central nervous system.
It is also explored in antimicrobial and antiviral research, showing promise against certain RNA viruses. Additionally, imidazo[1,2-a]pyrimidine derivatives are investigated for anticancer properties, especially as kinase inhibitors that interfere with tumor cell proliferation. Its versatility in forming stable heterocyclic compounds supports its use in medicinal chemistry and the synthesis of bioactive molecules.
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