JNJ0966
10mM in DMSO
- Product Code: 201305
CAS:
315705-75-0
| Molecular Weight: | 360.45 g./mol | Molecular Formula: | C₁₆H₁₆N₄O₂S₂ |
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| Density: | Storage Condition: | -20°C |
Product Description:
JNJ0966 is primarily used in scientific research for its ability to selectively inhibit the deubiquitinase enzyme USP1. This inhibition plays a key role in disrupting DNA repair pathways, particularly in cancer cells that rely on the USP1-UAF1 complex for survival. Due to this mechanism, JNJ0966 is investigated as a potential therapeutic agent in oncology, especially in combination with DNA-damaging agents like chemotherapy or PARP inhibitors. It shows promise in enhancing the sensitivity of tumor cells to these treatments, making it a valuable tool in developing targeted cancer therapies. Its application is currently limited to preclinical studies, where it helps elucidate the role of USP1 in cellular processes and cancer progression.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,480.00 |
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JNJ0966
JNJ0966 is primarily used in scientific research for its ability to selectively inhibit the deubiquitinase enzyme USP1. This inhibition plays a key role in disrupting DNA repair pathways, particularly in cancer cells that rely on the USP1-UAF1 complex for survival. Due to this mechanism, JNJ0966 is investigated as a potential therapeutic agent in oncology, especially in combination with DNA-damaging agents like chemotherapy or PARP inhibitors. It shows promise in enhancing the sensitivity of tumor cells to these treatments, making it a valuable tool in developing targeted cancer therapies. Its application is currently limited to preclinical studies, where it helps elucidate the role of USP1 in cellular processes and cancer progression.
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