Ko143 hydrate
10mM in DMSO
- Product Code: 201404
CAS:
461054-93-3
| Molecular Weight: | 469.57 g./mol | Molecular Formula: | C₂₆H₃₅N₃O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD19053160 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Ko143 hydrate is widely used in cancer research due to its ability to inhibit the ABCG2 transporter, a protein involved in multidrug resistance. By blocking this transporter, Ko143 enhances the effectiveness of certain chemotherapy drugs that would otherwise be pumped out of cancer cells. This makes it a valuable tool in studies aiming to overcome drug resistance in tumors, particularly in breast, lung, and colon cancers. It is commonly applied in in vitro experiments to assess the role of ABCG2 in drug accumulation and cytotoxicity. Due to its specificity, Ko143 hydrate helps researchers distinguish ABCG2-mediated resistance from other resistance mechanisms, supporting the development of more effective combination therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,200.00 |
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Ko143 hydrate
Ko143 hydrate is widely used in cancer research due to its ability to inhibit the ABCG2 transporter, a protein involved in multidrug resistance. By blocking this transporter, Ko143 enhances the effectiveness of certain chemotherapy drugs that would otherwise be pumped out of cancer cells. This makes it a valuable tool in studies aiming to overcome drug resistance in tumors, particularly in breast, lung, and colon cancers. It is commonly applied in in vitro experiments to assess the role of ABCG2 in drug accumulation and cytotoxicity. Due to its specificity, Ko143 hydrate helps researchers distinguish ABCG2-mediated resistance from other resistance mechanisms, supporting the development of more effective combination therapies.
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