Kenpaullone
10mM in DMSO
- Product Code: 201410
CAS:
142273-20-9
| Molecular Weight: | 327.18 g./mol | Molecular Formula: | C₁₆H₁₁BrN₂O |
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| EC Number: | MDL Number: | MFCD02683595 | |
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| Density: | Storage Condition: | -20°C, Inert Gas |
Product Description:
Kenpaullone is primarily used in biomedical research for its ability to inhibit specific kinases involved in cell cycle regulation, particularly cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3). Its inhibitory action makes it a valuable tool in studying cell proliferation, neuronal differentiation, and apoptosis. Researchers use kenpaullone to probe signaling pathways in cancer cells, as it can induce cell cycle arrest and promote death in certain tumor lines. It has also been investigated for potential neuroprotective effects due to its impact on GSK-3, a kinase implicated in neurodegenerative conditions like Alzheimer's disease. Additionally, kenpaullone is employed in stem cell research to modulate differentiation pathways, especially in promoting neuronal lineage commitment. Its relatively selective kinase inhibition profile allows for targeted experimental manipulation in cellular and molecular studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿5,550.00 |
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Kenpaullone
Kenpaullone is primarily used in biomedical research for its ability to inhibit specific kinases involved in cell cycle regulation, particularly cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3). Its inhibitory action makes it a valuable tool in studying cell proliferation, neuronal differentiation, and apoptosis. Researchers use kenpaullone to probe signaling pathways in cancer cells, as it can induce cell cycle arrest and promote death in certain tumor lines. It has also been investigated for potential neuroprotective effects due to its impact on GSK-3, a kinase implicated in neurodegenerative conditions like Alzheimer's disease. Additionally, kenpaullone is employed in stem cell research to modulate differentiation pathways, especially in promoting neuronal lineage commitment. Its relatively selective kinase inhibition profile allows for targeted experimental manipulation in cellular and molecular studies.
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