KN-93
10mM in DMSO
- Product Code: 201422
CAS:
139298-40-1
| Molecular Weight: | 501.04 g./mol | Molecular Formula: | C₂₆H₂₉ClN₂O₄S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00236424 | |
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| Density: | Storage Condition: | -20°C |
Product Description:
KN-93 is widely used in biomedical research to investigate the role of calcium/calmodulin-dependent protein kinase II (CaMKII) in cellular signaling pathways. It acts as a selective inhibitor of CaMKII, making it a valuable tool for studying processes such as neuronal plasticity, cardiac function, and immune responses where CaMKII activity is critical. Researchers apply KN-93 in models of heart disease to explore arrhythmias and hypertrophy, as CaMKII overactivation is linked to these conditions. In neuroscience, it helps examine synaptic transmission, learning, and memory by blocking CaMKII-mediated phosphorylation events. KN-93 is also used in studies of inflammation and apoptosis, where it can modulate cell survival pathways. Due to its cell-permeable nature, it is effective in both in vitro and in vivo experimental systems, allowing for broad application across physiological research areas.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,480.00 |
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KN-93
KN-93 is widely used in biomedical research to investigate the role of calcium/calmodulin-dependent protein kinase II (CaMKII) in cellular signaling pathways. It acts as a selective inhibitor of CaMKII, making it a valuable tool for studying processes such as neuronal plasticity, cardiac function, and immune responses where CaMKII activity is critical. Researchers apply KN-93 in models of heart disease to explore arrhythmias and hypertrophy, as CaMKII overactivation is linked to these conditions. In neuroscience, it helps examine synaptic transmission, learning, and memory by blocking CaMKII-mediated phosphorylation events. KN-93 is also used in studies of inflammation and apoptosis, where it can modulate cell survival pathways. Due to its cell-permeable nature, it is effective in both in vitro and in vivo experimental systems, allowing for broad application across physiological research areas.
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