KPT-185
10mM in DMSO
- Product Code: 201424
CAS:
1333151-73-7
| Molecular Weight: | 355.31 g./mol | Molecular Formula: | C₁₆H₁₆F₃N₃O₃ |
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| Density: | Storage Condition: | -20°C |
Product Description:
KPT-185 is primarily used in biochemical and pharmaceutical research as a selective inhibitor of nuclear export proteins, particularly XPO1 (exportin-1). It demonstrates potent anti-cancer activity by promoting the retention of tumor suppressor proteins and growth regulators within the nucleus, leading to cell cycle arrest and apoptosis in cancer cells. It is commonly employed in studies related to hematological malignancies and solid tumors to evaluate the effects of blocking nuclear export pathways. Due to its role in modulating key cellular processes, KPT-185 serves as a valuable tool compound in target validation and mechanism-of-action studies for novel cancer therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,480.00 |
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KPT-185
KPT-185 is primarily used in biochemical and pharmaceutical research as a selective inhibitor of nuclear export proteins, particularly XPO1 (exportin-1). It demonstrates potent anti-cancer activity by promoting the retention of tumor suppressor proteins and growth regulators within the nucleus, leading to cell cycle arrest and apoptosis in cancer cells. It is commonly employed in studies related to hematological malignancies and solid tumors to evaluate the effects of blocking nuclear export pathways. Due to its role in modulating key cellular processes, KPT-185 serves as a valuable tool compound in target validation and mechanism-of-action studies for novel cancer therapies.
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