Ki20227
10mM in DMSO
- Product Code: 201431
CAS:
623142-96-1
| Molecular Weight: | 480.54 g./mol | Molecular Formula: | C₂₄H₂₄N₄O₅S |
|---|---|---|---|
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| Density: | Storage Condition: | -20°C |
Product Description:
Ki20227 is a selective inhibitor of the TGF-β receptor kinase, primarily used in research settings to study signaling pathways involved in fibrosis, cancer progression, and epithelial-mesenchymal transition (EMT). It is commonly applied in cellular and molecular biology experiments to suppress TGF-β-mediated responses, helping to elucidate the role of this pathway in disease mechanisms. Due to its specificity, Ki20227 is valuable in screening studies aimed at developing anti-fibrotic or anti-cancer therapies. It is also used in combination with other inhibitors to modulate stem cell differentiation, particularly in induced pluripotent stem cell (iPSC) cultures, where blocking TGF-β signaling supports more controlled lineage specification.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿8,200.00 |
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Ki20227
Ki20227 is a selective inhibitor of the TGF-β receptor kinase, primarily used in research settings to study signaling pathways involved in fibrosis, cancer progression, and epithelial-mesenchymal transition (EMT). It is commonly applied in cellular and molecular biology experiments to suppress TGF-β-mediated responses, helping to elucidate the role of this pathway in disease mechanisms. Due to its specificity, Ki20227 is valuable in screening studies aimed at developing anti-fibrotic or anti-cancer therapies. It is also used in combination with other inhibitors to modulate stem cell differentiation, particularly in induced pluripotent stem cell (iPSC) cultures, where blocking TGF-β signaling supports more controlled lineage specification.
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