KY02111
98%
- Product Code: 201471
CAS:
1118807-13-8
| Molecular Weight: | 376.86 g./mol | Molecular Formula: | C₁₈H₁₇ClN₂O₃S |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | Room temperature, dry, sealed |
Product Description:
KY02111 is a potent and selective inhibitor of Wnt signaling pathway, specifically targeting the interaction between tankyrase and Axin. This compound is widely used in cancer research due to its ability to stabilize Axin and promote β-catenin degradation, thereby suppressing the oncogenic Wnt/β-catenin signaling that is often hyperactive in various cancers, including colorectal and liver cancers.
It serves as a valuable tool in studying the regulation of the Wnt pathway and has shown promise in preclinical models for inhibiting the growth of tumor cells with minimal effects on normal cells. KY02111 is also utilized in stem cell research to modulate differentiation and self-renewal processes governed by Wnt signaling. Its application extends to regenerative medicine and drug discovery, where precise control of Wnt activity is essential.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 10mg | 10-20 days | ฿540.00 |
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| 50mg | 10-20 days | ฿2,292.00 |
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| 250mg | 10-20 days | ฿6,606.00 |
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| 1g | 10-20 days | ฿16,410.00 |
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| 5g | 10-20 days | ฿44,046.00 |
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| bulk | 10-20 days | ฿0.00 |
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KY02111
KY02111 is a potent and selective inhibitor of Wnt signaling pathway, specifically targeting the interaction between tankyrase and Axin. This compound is widely used in cancer research due to its ability to stabilize Axin and promote β-catenin degradation, thereby suppressing the oncogenic Wnt/β-catenin signaling that is often hyperactive in various cancers, including colorectal and liver cancers.
It serves as a valuable tool in studying the regulation of the Wnt pathway and has shown promise in preclinical models for inhibiting the growth of tumor cells with minimal effects on normal cells. KY02111 is also utilized in stem cell research to modulate differentiation and self-renewal processes governed by Wnt signaling. Its application extends to regenerative medicine and drug discovery, where precise control of Wnt activity is essential.
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