Lomeguatrib
10mM in DMSO
- Product Code: 201830
CAS:
192441-08-0
| Molecular Weight: | 326.17 g./mol | Molecular Formula: | C₁₀H₈BrN₅OS |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09837804 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used in research for enhancing the effectiveness of alkylating agents in cancer therapy by inhibiting the DNA repair protein O6-alkylguanine-DNA alkyltransferase (AGT). This inhibition helps prevent tumor cells from repairing DNA damage induced by chemotherapy, thereby increasing cancer cell death. Investigated primarily in combination with drugs like temozolomide for treating resistant tumors, including gliomas and melanomas. Shows potential in overcoming chemoresistance in malignancies with high AGT expression.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿5,500.00 |
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Lomeguatrib
Used in research for enhancing the effectiveness of alkylating agents in cancer therapy by inhibiting the DNA repair protein O6-alkylguanine-DNA alkyltransferase (AGT). This inhibition helps prevent tumor cells from repairing DNA damage induced by chemotherapy, thereby increasing cancer cell death. Investigated primarily in combination with drugs like temozolomide for treating resistant tumors, including gliomas and melanomas. Shows potential in overcoming chemoresistance in malignancies with high AGT expression.
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