Lys05
10mM in DMSO
- Product Code: 201880
CAS:
1391426-24-6
| Molecular Weight: | 549.75 g./mol | Molecular Formula: | C₂₃H₂₆Cl₅N₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28963913 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Lys05 is a potent lysosomotropic agent that functions as an autophagy inhibitor. It is widely used in cancer research due to its ability to disrupt lysosomal function and enhance the cytotoxic effects of various anticancer therapies. By accumulating within lysosomes and increasing their pH, Lys05 impairs autophagic degradation, a process that cancer cells often rely on to survive under stress. This makes it a valuable tool in overcoming resistance to chemotherapy and radiation.
It has shown promise in preclinical studies when combined with other agents, particularly in hard-to-treat cancers such as pancreatic and breast cancer. Its ability to block autophagy more effectively than earlier inhibitors like chloroquine has made it a compound of interest in developing new therapeutic strategies. Additionally, Lys05 is used in cellular biology research to study the role of autophagy in disease mechanisms, including neurodegeneration and infectious diseases.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,480.00 |
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Lys05
Lys05 is a potent lysosomotropic agent that functions as an autophagy inhibitor. It is widely used in cancer research due to its ability to disrupt lysosomal function and enhance the cytotoxic effects of various anticancer therapies. By accumulating within lysosomes and increasing their pH, Lys05 impairs autophagic degradation, a process that cancer cells often rely on to survive under stress. This makes it a valuable tool in overcoming resistance to chemotherapy and radiation.
It has shown promise in preclinical studies when combined with other agents, particularly in hard-to-treat cancers such as pancreatic and breast cancer. Its ability to block autophagy more effectively than earlier inhibitors like chloroquine has made it a compound of interest in developing new therapeutic strategies. Additionally, Lys05 is used in cellular biology research to study the role of autophagy in disease mechanisms, including neurodegeneration and infectious diseases.
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