LY-3475070

99%

  • Product Code: 202782
  CAS:    2375815-63-5
Molecular Weight: 286.34 g./mol Molecular Formula: C₁₅H₁₈N₄O₂
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Density: Storage Condition: -20°C
Product Description: LY-3475070 is a selective kappa opioid receptor (KOR) antagonist being investigated primarily for its potential in treating psychiatric and neurological disorders. It has shown promise in preclinical studies for modulating stress-related behaviors and depressive symptoms without the side effects commonly associated with traditional antidepressants. Due to its ability to cross the blood-brain barrier effectively, it is being explored as a therapeutic agent in mood disorders, including major depressive disorder and anxiety. Additionally, its KOR antagonism may help reduce dysphoria and anhedonia, making it a candidate for conditions involving reward pathway dysfunction. Research is ongoing to evaluate its efficacy in substance use disorders, where KOR activation plays a role in drug-seeking behavior and relapse. Its development highlights a targeted approach to mental health treatment with improved tolerability and faster onset of action.
Sizes / Availability / Pricing:
Size Availability Price Quantity
5mg 10-20 days $413.28
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25mg 10-20 days $1,051.71
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100mg 10-20 days $3,038.47
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LY-3475070
LY-3475070 is a selective kappa opioid receptor (KOR) antagonist being investigated primarily for its potential in treating psychiatric and neurological disorders. It has shown promise in preclinical studies for modulating stress-related behaviors and depressive symptoms without the side effects commonly associated with traditional antidepressants. Due to its ability to cross the blood-brain barrier effectively, it is being explored as a therapeutic agent in mood disorders, including major depressive disorder and anxiety. Additionally, its KOR antagonism may help reduce dysphoria and anhedonia, making it a candidate for conditions involving reward pathway dysfunction. Research is ongoing to evaluate its efficacy in substance use disorders, where KOR activation plays a role in drug-seeking behavior and relapse. Its development highlights a targeted approach to mental health treatment with improved tolerability and faster onset of action.
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