Methyl 5-iodo-1H-indazole-3-carboxylate
98%
- Product Code: 202886
CAS:
1079-47-6
| Molecular Weight: | 302.06 g./mol | Molecular Formula: | C₉H₇IN₂O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD07371578 | |
| Melting Point: | 264 °C | Boiling Point: | 421.4±25.0 °C(Predicted) |
| Density: | 1.948±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry, light-proof |
Product Description:
Used primarily as a key intermediate in the synthesis of bioactive compounds, particularly in pharmaceutical research. It serves as a building block for developing kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The presence of the iodine atom allows for further functionalization via cross-coupling reactions, such as Suzuki or Heck reactions, enabling rapid diversification in drug discovery programs. Its indazole core is valued for mimicking purine structures, enhancing binding affinity to enzyme active sites. Commonly employed in the development of selective inhibitors for proteins like B-Raf, JAK, or CDK, it supports the creation of potential therapeutics in oncology and autoimmune disorders. Also utilized in radiolabeling studies and probe development for biochemical assays due to the iodine moiety.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿21,190.00 |
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Methyl 5-iodo-1H-indazole-3-carboxylate
Used primarily as a key intermediate in the synthesis of bioactive compounds, particularly in pharmaceutical research. It serves as a building block for developing kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The presence of the iodine atom allows for further functionalization via cross-coupling reactions, such as Suzuki or Heck reactions, enabling rapid diversification in drug discovery programs. Its indazole core is valued for mimicking purine structures, enhancing binding affinity to enzyme active sites. Commonly employed in the development of selective inhibitors for proteins like B-Raf, JAK, or CDK, it supports the creation of potential therapeutics in oncology and autoimmune disorders. Also utilized in radiolabeling studies and probe development for biochemical assays due to the iodine moiety.
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