3-Methyl-2-thioxo-2,3,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one
97%
- Product Code: 203435
CAS:
38201-61-5
| Molecular Weight: | 252.35 g./mol | Molecular Formula: | C₁₁H₁₂N₂OS₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00128348 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting cyclin-dependent kinases (CDKs) involved in cancer cell proliferation. Its structure supports high binding affinity to ATP-binding sites in kinases, making it valuable in developing anti-tumor agents. Also explored in the design of selective inhibitors for inflammatory and neurodegenerative diseases due to its ability to cross the blood-brain barrier. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved metabolic stability and potency.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿3,610.00 |
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| 1.000 | 10-20 days | ฿16,520.00 |
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| 0.250 | 10-20 days | ฿6,130.00 |
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3-Methyl-2-thioxo-2,3,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one
Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting cyclin-dependent kinases (CDKs) involved in cancer cell proliferation. Its structure supports high binding affinity to ATP-binding sites in kinases, making it valuable in developing anti-tumor agents. Also explored in the design of selective inhibitors for inflammatory and neurodegenerative diseases due to its ability to cross the blood-brain barrier. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved metabolic stability and potency.
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