Mal-amido-PEG28-NHS
- Product Code: 203585
CAS:
2229707-72-4
| Molecular Weight: | 1570.76 g./mol | Molecular Formula: | C₇₀H₁₂₇N₃O₃₅ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in bioconjugation to link molecules with high specificity, particularly in the development of antibody-drug conjugates (ADCs). The NHS ester reacts efficiently with primary amines on proteins or peptides, forming stable amide bonds. The PEG28 spacer provides enhanced solubility and reduces aggregation, while the maleimide group allows for subsequent conjugation to thiol-containing molecules, such as cysteine residues in antibodies or thiolated biomolecules. Commonly applied in pharmaceutical research, targeted therapies, and diagnostic probes where controlled, two-step coupling is required. Its long PEG chain improves pharmacokinetic properties by increasing circulation time and reducing immunogenicity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | $2,922.23 |
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Mal-amido-PEG28-NHS
Used in bioconjugation to link molecules with high specificity, particularly in the development of antibody-drug conjugates (ADCs). The NHS ester reacts efficiently with primary amines on proteins or peptides, forming stable amide bonds. The PEG28 spacer provides enhanced solubility and reduces aggregation, while the maleimide group allows for subsequent conjugation to thiol-containing molecules, such as cysteine residues in antibodies or thiolated biomolecules. Commonly applied in pharmaceutical research, targeted therapies, and diagnostic probes where controlled, two-step coupling is required. Its long PEG chain improves pharmacokinetic properties by increasing circulation time and reducing immunogenicity.
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