Mal-PEG2-PFP ester
98%
- Product Code: 203590
CAS:
1807512-47-5
| Molecular Weight: | 423.29 g./mol | Molecular Formula: | C₁₇H₁₄F₅NO₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD26127799 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used in bioconjugation to link polyethylene glycol (PEG) chains to biomolecules such as proteins, peptides, or antibodies. The maleimide group reacts selectively with thiol groups (-SH), commonly found in cysteine residues, enabling site-specific modification. The PFP ester end reacts efficiently with primary amines (-NH2) on biomolecules, forming stable amide bonds. This dual functionality allows for sequential conjugation strategies, useful in developing PEGylated therapeutics, diagnostic probes, and targeted drug delivery systems. The PEG2 spacer improves solubility and reduces steric hindrance, enhancing reaction efficiency and stability of the final conjugate.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 10mg | 10-20 days | $219.56 |
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| 50mg | 10-20 days | $835.17 |
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Mal-PEG2-PFP ester
Used in bioconjugation to link polyethylene glycol (PEG) chains to biomolecules such as proteins, peptides, or antibodies. The maleimide group reacts selectively with thiol groups (-SH), commonly found in cysteine residues, enabling site-specific modification. The PFP ester end reacts efficiently with primary amines (-NH2) on biomolecules, forming stable amide bonds. This dual functionality allows for sequential conjugation strategies, useful in developing PEGylated therapeutics, diagnostic probes, and targeted drug delivery systems. The PEG2 spacer improves solubility and reduces steric hindrance, enhancing reaction efficiency and stability of the final conjugate.
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| Stable in pH range | - |
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