Mal-amido-(CH2COOH)2
99%
- Product Code: 203972
CAS:
207613-14-7
| Molecular Weight: | 284.22 g./mol | Molecular Formula: | C₁₁H₁₂N₂O₇ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD34469576 | |
| Melting Point: | Boiling Point: | 620.2±50.0 °C(Predicted) | |
| Density: | 1.580±0.06 g/cm3(Predicted) | Storage Condition: | -20°C |
Product Description:
Used as a bifunctional crosslinking agent in bioconjugation, particularly for attaching fluorescent dyes, drugs, or other functional molecules to proteins, peptides, or nanoparticles. The maleimide group selectively reacts with thiol groups (-SH) under mild conditions, forming stable thioether bonds, while the two carboxylic acid groups allow further activation and coupling to amine-containing molecules via EDC/NHS chemistry. Commonly employed in the development of antibody-drug conjugates (ADCs), targeted therapies, and diagnostic probes. Its hydrophilic nature helps improve solubility and reduce aggregation in aqueous biological systems.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | €814.05 |
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Mal-amido-(CH2COOH)2
Used as a bifunctional crosslinking agent in bioconjugation, particularly for attaching fluorescent dyes, drugs, or other functional molecules to proteins, peptides, or nanoparticles. The maleimide group selectively reacts with thiol groups (-SH) under mild conditions, forming stable thioether bonds, while the two carboxylic acid groups allow further activation and coupling to amine-containing molecules via EDC/NHS chemistry. Commonly employed in the development of antibody-drug conjugates (ADCs), targeted therapies, and diagnostic probes. Its hydrophilic nature helps improve solubility and reduce aggregation in aqueous biological systems.
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