MC-Val-Cit-PAB
10mM in DMSO
- Product Code: 204212
CAS:
159857-80-4
| Molecular Weight: | 572.65 g./mol | Molecular Formula: | C₂₈H₄₀N₆O₇ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, dry, away from light |
Product Description:
Used as a linker in antibody-drug conjugates (ADCs) to connect cytotoxic drugs to monoclonal antibodies. Its design allows for stable circulation in the bloodstream while enabling the release of the active drug inside target cells, particularly cancer cells. The linker is cleaved by intracellular enzymes such as cathepsin B in the lysosome, ensuring targeted drug delivery. This selective release minimizes damage to healthy tissues and enhances the therapeutic index of ADCs. Widely applied in oncology drug development due to its reliability and efficiency in payload delivery.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿5,350.00 |
+
-
|
MC-Val-Cit-PAB
Used as a linker in antibody-drug conjugates (ADCs) to connect cytotoxic drugs to monoclonal antibodies. Its design allows for stable circulation in the bloodstream while enabling the release of the active drug inside target cells, particularly cancer cells. The linker is cleaved by intracellular enzymes such as cathepsin B in the lysosome, ensuring targeted drug delivery. This selective release minimizes damage to healthy tissues and enhances the therapeutic index of ADCs. Widely applied in oncology drug development due to its reliability and efficiency in payload delivery.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :