ML240
10mM in DMSO
- Product Code: 204241
CAS:
1346527-98-7
| Molecular Weight: | 396.44 g./mol | Molecular Formula: | C₂₃H₂₀N₆O |
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| Density: | Storage Condition: | -20°C |
Product Description:
ML240 is a selective inhibitor of p97 (also known as VCP), a key ATPase involved in ubiquitin-proteasome system pathways. It is primarily used in research settings to study protein degradation mechanisms, particularly in the context of endoplasmic reticulum-associated degradation (ERAD). By inhibiting p97, ML240 induces accumulation of ubiquitinated proteins and triggers endoplasmic reticulum stress, leading to apoptosis in certain cancer cell lines. This makes it a valuable tool for investigating cancer cell survival pathways and the potential of p97 as a therapeutic target in oncology. Its application is largely confined to in vitro studies, where it helps elucidate the role of p97 in cellular homeostasis and disease progression.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿6,660.00 |
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ML240
ML240 is a selective inhibitor of p97 (also known as VCP), a key ATPase involved in ubiquitin-proteasome system pathways. It is primarily used in research settings to study protein degradation mechanisms, particularly in the context of endoplasmic reticulum-associated degradation (ERAD). By inhibiting p97, ML240 induces accumulation of ubiquitinated proteins and triggers endoplasmic reticulum stress, leading to apoptosis in certain cancer cell lines. This makes it a valuable tool for investigating cancer cell survival pathways and the potential of p97 as a therapeutic target in oncology. Its application is largely confined to in vitro studies, where it helps elucidate the role of p97 in cellular homeostasis and disease progression.
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