4-(Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester
10mM in DMSO
- Product Code: 204263
CAS:
64987-85-5
| Molecular Weight: | 334.33 g./mol | Molecular Formula: | C₁₆H₁₈N₂O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00009634 | |
| Melting Point: | 180-182 °C(lit.) | Boiling Point: | |
| Density: | Storage Condition: | -20°C, avoiding light |
Product Description:
Widely used in bioconjugation, this compound enables efficient crosslinking between thiol-containing molecules and primary amines. Its maleimide group selectively reacts with sulfhydryl groups, while the NHS ester reacts with amine groups, making it ideal for coupling peptides, proteins, and antibodies. Commonly applied in the development of antibody-drug conjugates (ADCs), it helps attach cytotoxic agents to targeting antibodies with high specificity. It is also used in immobilizing biomolecules onto surfaces such as biosensors, hydrogels, and nanoparticles. Due to its stable amide bond formation and selective reactivity, it supports controlled conjugation in complex biological environments, enhancing reproducibility in diagnostic and therapeutic applications.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿1,850.00 |
+
-
|
4-(Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester
Widely used in bioconjugation, this compound enables efficient crosslinking between thiol-containing molecules and primary amines. Its maleimide group selectively reacts with sulfhydryl groups, while the NHS ester reacts with amine groups, making it ideal for coupling peptides, proteins, and antibodies. Commonly applied in the development of antibody-drug conjugates (ADCs), it helps attach cytotoxic agents to targeting antibodies with high specificity. It is also used in immobilizing biomolecules onto surfaces such as biosensors, hydrogels, and nanoparticles. Due to its stable amide bond formation and selective reactivity, it supports controlled conjugation in complex biological environments, enhancing reproducibility in diagnostic and therapeutic applications.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :