MM-102
10mM in DMSO
- Product Code: 204539
CAS:
1417329-24-8
| Molecular Weight: | 669.8 g./mol | Molecular Formula: | C₃₅H₄₉F₂N₇O₄ |
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| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in research settings as a potent and selective inhibitor of the menin-MLL (mixed lineage leukemia) protein-protein interaction. This inhibition is critical in studying acute leukemias, especially those involving MLL gene rearrangements. By disrupting the menin-MLL interaction, it suppresses the expression of key leukemogenic genes such as HOXA9 and MEIS1, leading to reduced proliferation and induction of apoptosis in MLL-rearranged leukemia cells. Due to its cell permeability and stability, it is widely used in cellular and in vivo models to validate menin as a therapeutic target and to explore potential pathways for treating MLL-fusion-driven cancers. It also serves as a lead compound in the development of targeted cancer therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿19,900.00 |
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MM-102
Used primarily in research settings as a potent and selective inhibitor of the menin-MLL (mixed lineage leukemia) protein-protein interaction. This inhibition is critical in studying acute leukemias, especially those involving MLL gene rearrangements. By disrupting the menin-MLL interaction, it suppresses the expression of key leukemogenic genes such as HOXA9 and MEIS1, leading to reduced proliferation and induction of apoptosis in MLL-rearranged leukemia cells. Due to its cell permeability and stability, it is widely used in cellular and in vivo models to validate menin as a therapeutic target and to explore potential pathways for treating MLL-fusion-driven cancers. It also serves as a lead compound in the development of targeted cancer therapies.
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