MonoMethyl auristatin E
10mM in DMSO
- Product Code: 204544
CAS:
474645-27-7
| Molecular Weight: | 718 g./mol | Molecular Formula: | C₃₉H₆₇N₅O₇ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28400134 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used as a cytotoxic payload in antibody-drug conjugates (ADCs) for targeted cancer therapy. It inhibits cell division by blocking microtubule polymerization, leading to apoptosis in tumor cells. Due to its high potency, it is effective at low concentrations when delivered selectively to cancer cells via monoclonal antibodies. Commonly employed in treatments for hematological malignancies and solid tumors.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | $286.10 |
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MonoMethyl auristatin E
Used as a cytotoxic payload in antibody-drug conjugates (ADCs) for targeted cancer therapy. It inhibits cell division by blocking microtubule polymerization, leading to apoptosis in tumor cells. Due to its high potency, it is effective at low concentrations when delivered selectively to cancer cells via monoclonal antibodies. Commonly employed in treatments for hematological malignancies and solid tumors.
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