Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoate
95%
- Product Code: 206785
CAS:
1045795-70-7
| Molecular Weight: | 330.11 g./mol | Molecular Formula: | C₁₅H₁₈BF₃O₄ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 379.5±42.0°C | |
| Density: | Storage Condition: | 2-8°C |
Product Description:
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable for constructing biaryl and heterobiaryl systems. The presence of the trifluoromethyl group enhances the metabolic stability and lipophilicity of target molecules, which is advantageous in drug design. Additionally, the ester functionality allows for further derivatization, such as hydrolysis or reduction, enabling versatile downstream modifications. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where controlled structure and electronic properties are critical.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿1,020.00 |
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| 1.000 G | 10-20 days | ฿4,020.00 |
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| 5.000 G | 10-20 days | ฿20,010.00 |
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| 25.000 G | 10-20 days | ฿78,820.00 |
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Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoate
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable for constructing biaryl and heterobiaryl systems. The presence of the trifluoromethyl group enhances the metabolic stability and lipophilicity of target molecules, which is advantageous in drug design. Additionally, the ester functionality allows for further derivatization, such as hydrolysis or reduction, enabling versatile downstream modifications. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where controlled structure and electronic properties are critical.
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