2-Methoxypyrimidine-5-boronic acid pinacol ester
98%
- Product Code: 208552
CAS:
1052686-60-8
| Molecular Weight: | 236.07 g./mol | Molecular Formula: | C₁₁H₁₇BN₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD13182190 | |
| Melting Point: | Boiling Point: | 354.3±34.0℃ at 760 mmHg | |
| Density: | Storage Condition: | 2-8℃, inert gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester group facilitates efficient and selective coupling with aryl or heteroaryl halides under mild conditions. Commonly employed in the development of bioactive molecules, including drug candidates containing pyrimidine scaffolds. The methoxy group enhances solubility and can influence electronic properties, improving reaction yields and selectivity. Stable and easy to handle, making it suitable for automated synthesis and library generation in medicinal chemistry.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿1,780.00 |
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| 250mg | 10-20 days | ฿2,720.00 |
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| 1g | 10-20 days | ฿10,390.00 |
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| 5g | 10-20 days | ฿39,720.00 |
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2-Methoxypyrimidine-5-boronic acid pinacol ester
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester group facilitates efficient and selective coupling with aryl or heteroaryl halides under mild conditions. Commonly employed in the development of bioactive molecules, including drug candidates containing pyrimidine scaffolds. The methoxy group enhances solubility and can influence electronic properties, improving reaction yields and selectivity. Stable and easy to handle, making it suitable for automated synthesis and library generation in medicinal chemistry.
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