Methyl 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate
≥95%
- Product Code: 209236
CAS:
947249-44-7
| Molecular Weight: | 278.11 g./mol | Molecular Formula: | C₁₃H₁₉BN₂O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD12923412 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, protected from light, stored in inert gas |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides under palladium catalysis. The presence of both amino and ester functional groups allows further derivatization, making it valuable in the development of nitrogen-containing heterocyclic systems found in drug candidates. Commonly employed in medicinal chemistry for constructing libraries of compounds targeting kinase inhibition and other therapeutic areas.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿2,850.00 |
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| 250mg | 10-20 days | ฿4,040.00 |
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| 1g | 10-20 days | ฿16,140.00 |
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Methyl 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides under palladium catalysis. The presence of both amino and ester functional groups allows further derivatization, making it valuable in the development of nitrogen-containing heterocyclic systems found in drug candidates. Commonly employed in medicinal chemistry for constructing libraries of compounds targeting kinase inhibition and other therapeutic areas.
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