(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

97%

  • Product Code: 209695
  CAS:    1448297-52-6
Molecular Weight: 430.56 g./mol Molecular Formula: C₂₂H₃₀N₄O₃S
EC Number: MDL Number: MFCD29049827
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used in pharmaceutical research as a potent and selective inhibitor of dipeptidyl peptidase-4 (DPP-4), this compound plays a key role in the development of treatments for type 2 diabetes. By inhibiting DPP-4, it enhances the activity of incretin hormones such as GLP-1, leading to improved glucose control, increased insulin secretion, and reduced glucagon levels in a glucose-dependent manner. Its structure supports high oral bioavailability and prolonged duration of action, making it a valuable candidate for once-daily dosing in antidiabetic therapies. It is also studied for potential anti-inflammatory and cardioprotective effects associated with DPP-4 inhibition.
Sizes / Availability / Pricing:
Size Availability Price Quantity
50mg 10-20 days $19.95
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250mg 10-20 days $41.50
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1g 10-20 days $126.90
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5g 10-20 days $454.94
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25g 10-20 days $1,867.65
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(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Used in pharmaceutical research as a potent and selective inhibitor of dipeptidyl peptidase-4 (DPP-4), this compound plays a key role in the development of treatments for type 2 diabetes. By inhibiting DPP-4, it enhances the activity of incretin hormones such as GLP-1, leading to improved glucose control, increased insulin secretion, and reduced glucagon levels in a glucose-dependent manner. Its structure supports high oral bioavailability and prolonged duration of action, making it a valuable candidate for once-daily dosing in antidiabetic therapies. It is also studied for potential anti-inflammatory and cardioprotective effects associated with DPP-4 inhibition.
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