(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
97%
- Product Code: 209695
CAS:
1448297-52-6
Molecular Weight: | 430.56 g./mol | Molecular Formula: | C₂₂H₃₀N₄O₃S |
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EC Number: | MDL Number: | MFCD29049827 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of dipeptidyl peptidase-4 (DPP-4), this compound plays a key role in the development of treatments for type 2 diabetes. By inhibiting DPP-4, it enhances the activity of incretin hormones such as GLP-1, leading to improved glucose control, increased insulin secretion, and reduced glucagon levels in a glucose-dependent manner. Its structure supports high oral bioavailability and prolonged duration of action, making it a valuable candidate for once-daily dosing in antidiabetic therapies. It is also studied for potential anti-inflammatory and cardioprotective effects associated with DPP-4 inhibition.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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50mg | 10-20 days | $19.95 |
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250mg | 10-20 days | $41.50 |
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1g | 10-20 days | $126.90 |
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5g | 10-20 days | $454.94 |
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25g | 10-20 days | $1,867.65 |
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(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Used in pharmaceutical research as a potent and selective inhibitor of dipeptidyl peptidase-4 (DPP-4), this compound plays a key role in the development of treatments for type 2 diabetes. By inhibiting DPP-4, it enhances the activity of incretin hormones such as GLP-1, leading to improved glucose control, increased insulin secretion, and reduced glucagon levels in a glucose-dependent manner. Its structure supports high oral bioavailability and prolonged duration of action, making it a valuable candidate for once-daily dosing in antidiabetic therapies. It is also studied for potential anti-inflammatory and cardioprotective effects associated with DPP-4 inhibition.
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