1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole
98%
- Product Code: 209768
CAS:
1025719-23-6
| Molecular Weight: | 276.06 g./mol | Molecular Formula: | C₁₁H₁₆BF₃N₂O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD12022323 | |
| Melting Point: | 66-67°C | Boiling Point: | |
| Density: | Storage Condition: | -20°C, sealed, dry |
Product Description:
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in medicinal chemistry for constructing complex molecules. The presence of trifluoromethyl and methyl groups enhances electronic and metabolic stability in target compounds, often improving bioavailability and biological activity. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where increased lipophilicity and resistance to oxidative degradation are required.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿960.00 |
+
-
|
| 1g | 10-20 days | ฿2,400.00 |
+
-
|
| 5g | 10-20 days | ฿9,590.00 |
+
-
|
| 10g | 10-20 days | ฿18,800.00 |
+
-
|
| 25g | 10-20 days | ฿47,000.00 |
+
-
|
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in medicinal chemistry for constructing complex molecules. The presence of trifluoromethyl and methyl groups enhances electronic and metabolic stability in target compounds, often improving bioavailability and biological activity. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where increased lipophilicity and resistance to oxidative degradation are required.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :