Methyl 2-((tert-butoxycarbonyl)amino)-2-methylpropanoate

98%

  • Product Code: 210186
  CAS:    84758-55-4
Molecular Weight: 217.26 g./mol Molecular Formula: C₁₀H₁₉NO₄
EC Number: MDL Number: MFCD20484740
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry, sealed
Product Description: Used as a protected amino acid derivative in peptide synthesis, particularly in solid-phase and solution-phase methods. The tert-butoxycarbonyl (Boc) group serves as a protecting group for the amine functionality, preventing unwanted reactions during coupling steps. The methyl ester allows for further functionalization or acts as a temporary protecting group for the carboxylic acid. Its sterically hindered alpha-methyl group helps reduce epimerization and increases stability during activation and coupling. Commonly employed in the preparation of complex peptides, peptidomimetics, and pharmaceutical intermediates where controlled stepwise assembly is required. Also useful in the synthesis of unnatural amino acids and bioactive molecules requiring selective deprotection and chain elongation.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days ฿290.00
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-
1g 10-20 days ฿510.00
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5g 10-20 days ฿1,360.00
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-
Methyl 2-((tert-butoxycarbonyl)amino)-2-methylpropanoate
Used as a protected amino acid derivative in peptide synthesis, particularly in solid-phase and solution-phase methods. The tert-butoxycarbonyl (Boc) group serves as a protecting group for the amine functionality, preventing unwanted reactions during coupling steps. The methyl ester allows for further functionalization or acts as a temporary protecting group for the carboxylic acid. Its sterically hindered alpha-methyl group helps reduce epimerization and increases stability during activation and coupling. Commonly employed in the preparation of complex peptides, peptidomimetics, and pharmaceutical intermediates where controlled stepwise assembly is required. Also useful in the synthesis of unnatural amino acids and bioactive molecules requiring selective deprotection and chain elongation.
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