5-[2-(4-Methylbiphenyl)]Tetrazole
98%
- Product Code: 212746
CAS:
120568-11-8
| Molecular Weight: | 236.27 g./mol | Molecular Formula: | C₁₄H₁₂N₄ |
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like candesartan and related sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. This compound plays a critical role in improving the potency and metabolic stability of these drugs. It is also employed in medicinal chemistry research for developing new bioactive molecules due to its favorable pharmacokinetic properties and ability to increase water solubility of drug candidates.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿6,830.00 |
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| 250mg | 10-20 days | ฿11,380.00 |
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| 1g | 10-20 days | ฿27,920.00 |
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5-[2-(4-Methylbiphenyl)]Tetrazole
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like candesartan and related sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. This compound plays a critical role in improving the potency and metabolic stability of these drugs. It is also employed in medicinal chemistry research for developing new bioactive molecules due to its favorable pharmacokinetic properties and ability to increase water solubility of drug candidates.
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