MB-07811
≥98%
- Product Code: 213040
CAS:
852948-13-1
| Molecular Weight: | 514.98 g./mol | Molecular Formula: | C₂₈H₃₂ClO₅P |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 77-82 °C | Boiling Point: | 660.6±55.0 °C(Predicted) |
| Density: | 1.27±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C |
Product Description:
Used in research settings as a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), an enzyme involved in cortisol metabolism. It is studied for its potential to modulate glucocorticoid activity, which may have implications in metabolic disorders such as type 2 diabetes, obesity, and insulin resistance. By inhibiting 11β-HSD1, it helps reduce local cortisol levels in tissues like liver and adipose, improving insulin sensitivity and glucose regulation in preclinical models. It serves as a tool compound for understanding glucocorticoid-related pathophysiology and evaluating therapeutic strategies targeting hormone regulation in metabolic disease.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1mg | 10-20 days | ฿12,350.00 |
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| 5mg | 10-20 days | ฿27,790.00 |
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-
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| 10mg | 10-20 days | ฿41,680.00 |
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|
MB-07811
Used in research settings as a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), an enzyme involved in cortisol metabolism. It is studied for its potential to modulate glucocorticoid activity, which may have implications in metabolic disorders such as type 2 diabetes, obesity, and insulin resistance. By inhibiting 11β-HSD1, it helps reduce local cortisol levels in tissues like liver and adipose, improving insulin sensitivity and glucose regulation in preclinical models. It serves as a tool compound for understanding glucocorticoid-related pathophysiology and evaluating therapeutic strategies targeting hormone regulation in metabolic disease.
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