2-Methyl-5-(1H-tetrazol-1-yl)benzoicacid
98%
- Product Code: 213869
CAS:
370560-58-0
| Molecular Weight: | 204.19 g./mol | Molecular Formula: | C₉H₈N₄O₂ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring mimics the carboxylic acid group in biological activity, enhancing binding to the AT1 receptor. Its structure serves as a key intermediate in pharmaceuticals like losartan and candesartan, contributing to improved metabolic stability and potency. Also employed in medicinal chemistry research for designing new bioactive molecules due to the tetrazole moiety’s ability to act as a pharmacophore.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿19,470.00 |
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2-Methyl-5-(1H-tetrazol-1-yl)benzoicacid
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring mimics the carboxylic acid group in biological activity, enhancing binding to the AT1 receptor. Its structure serves as a key intermediate in pharmaceuticals like losartan and candesartan, contributing to improved metabolic stability and potency. Also employed in medicinal chemistry research for designing new bioactive molecules due to the tetrazole moiety’s ability to act as a pharmacophore.
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