N-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
95%
- Product Code: 214782
CAS:
139554-72-6
| Molecular Weight: | 366.44 g./mol | Molecular Formula: | C₁₆H₂₂N₄O₄S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD02094223 | |
| Melting Point: | 123-129 °C | Boiling Point: | 743.5±55.0 °C(Predicted) |
| Density: | Storage Condition: | -20°C, Inert Gas |
Product Description:
Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows stable attachment between the antibody and the drug payload, improving pharmacokinetics and reducing off-target effects. The compound’s functional groups support conjugation chemistry, particularly through maleimide-thiol coupling, commonly used in bioconjugation. It helps maintain the integrity of the ADC in circulation while allowing efficient drug release inside the target cell.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1mg | 10-20 days | ฿2,720.00 |
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| 5mg | 10-20 days | ฿6,790.00 |
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| 10mg | 10-20 days | ฿10,160.00 |
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| 25mg | 10-20 days | ฿20,360.00 |
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| 100mg | 10-20 days | ฿48,800.00 |
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| 250mg | 10-20 days | ฿73,190.00 |
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| 50mg | 10-20 days | ฿32,530.00 |
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N-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows stable attachment between the antibody and the drug payload, improving pharmacokinetics and reducing off-target effects. The compound’s functional groups support conjugation chemistry, particularly through maleimide-thiol coupling, commonly used in bioconjugation. It helps maintain the integrity of the ADC in circulation while allowing efficient drug release inside the target cell.
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