N-benzoyl-2'-O-(tert-butyldimethylsilyl)cytidine
98%
- Product Code: 215318
CAS:
72687-01-5
| Molecular Weight: | 461.58 g./mol | Molecular Formula: | C₂₂H₃₁N₃O₆Si |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as an intermediate in the synthesis of oligonucleotides, particularly in the preparation of modified RNA strands for research and therapeutic applications. Its primary role is in the development of antisense oligonucleotides and small interfering RNA (siRNA) where selective protection of the 2'-hydroxyl group enhances stability and specificity during solid-phase synthesis. The tert-butyldimethylsilyl group provides steric protection, while the N-benzoyl moiety stabilizes the cytosine base, minimizing side reactions. This compound is essential in producing nucleic acid analogs with improved nuclease resistance and binding affinity, useful in gene silencing and molecular biology studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5g | 10-20 days | ฿20,000.00 |
+
-
|
N-benzoyl-2'-O-(tert-butyldimethylsilyl)cytidine
Used as an intermediate in the synthesis of oligonucleotides, particularly in the preparation of modified RNA strands for research and therapeutic applications. Its primary role is in the development of antisense oligonucleotides and small interfering RNA (siRNA) where selective protection of the 2'-hydroxyl group enhances stability and specificity during solid-phase synthesis. The tert-butyldimethylsilyl group provides steric protection, while the N-benzoyl moiety stabilizes the cytosine base, minimizing side reactions. This compound is essential in producing nucleic acid analogs with improved nuclease resistance and binding affinity, useful in gene silencing and molecular biology studies.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :