1-(Furan-2-ylmethyl)-5-oxo-N-(2-propoxy-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide

98%

  • Product Code: 215602
  CAS:    870760-17-1
Molecular Weight: 410.39 g./mol Molecular Formula: C₂₀H₂₁F₃N₂O₄
EC Number: MDL Number:
Melting Point: Boiling Point: 566.4±50.0 °C(Predicted)
Density: 1.339±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a key intermediate in the synthesis of sitagliptin, a pharmaceutical agent for the treatment of type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood glucose levels. Its structure supports high selectivity and potency in the final active pharmaceutical ingredient. Commonly employed in late-stage coupling reactions during manufacturing due to its stability and reactivity profile.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days €902.68
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250mg 10-20 days €1,534.20
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1-(Furan-2-ylmethyl)-5-oxo-N-(2-propoxy-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide
Used as a key intermediate in the synthesis of sitagliptin, a pharmaceutical agent for the treatment of type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood glucose levels. Its structure supports high selectivity and potency in the final active pharmaceutical ingredient. Commonly employed in late-stage coupling reactions during manufacturing due to its stability and reactivity profile.
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