6-Bromo-N-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)quinazolin-2-amine
97%
- Product Code: 215866
CAS:
2682115-60-0
| Molecular Weight: | 387.28 g./mol | Molecular Formula: | C₁₇H₁₉BrN₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD33022426 | |
| Melting Point: | Boiling Point: | 568.0±60.0 °C(Predicted) | |
| Density: | 1.58±0.1 g/cm3(Predicted) | Storage Condition: | Room temperature, away from light, dry |
Product Description:
Used in pharmaceutical research as a potent inhibitor of tyrosine kinases, particularly targeting EGFR (epidermal growth factor receptor) and HER2 pathways. It shows promise in the development of anticancer agents due to its ability to block signaling pathways involved in tumor growth and proliferation. Its structure allows for high selectivity and binding affinity, making it a valuable scaffold in optimizing kinase inhibitors for improved efficacy and reduced resistance in cancer therapy. Also investigated for blood-brain barrier penetration, supporting potential use in treating brain metastases.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿7,180.00 |
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| 0.250 | 10-20 days | ฿10,780.00 |
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| 1.000 | 10-20 days | ฿26,890.00 |
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6-Bromo-N-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)quinazolin-2-amine
Used in pharmaceutical research as a potent inhibitor of tyrosine kinases, particularly targeting EGFR (epidermal growth factor receptor) and HER2 pathways. It shows promise in the development of anticancer agents due to its ability to block signaling pathways involved in tumor growth and proliferation. Its structure allows for high selectivity and binding affinity, making it a valuable scaffold in optimizing kinase inhibitors for improved efficacy and reduced resistance in cancer therapy. Also investigated for blood-brain barrier penetration, supporting potential use in treating brain metastases.
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