4-Amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
98%
- Product Code: 215933
CAS:
942437-37-8
| Molecular Weight: | 354.38 g./mol | Molecular Formula: | C₁₉H₁₉FN₄O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD21337369 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of anaplastic lymphoma kinase (ALK). It shows promising activity against ALK-driven cancers, particularly non-small cell lung cancer (NSCLC) with ALK gene rearrangements. The compound effectively crosses the blood-brain barrier, making it valuable in treating brain metastases associated with ALK-positive tumors. Its high selectivity reduces off-target effects, improving therapeutic efficacy and patient tolerance in clinical settings.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | ฿2,570.00 |
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| 10mg | 10-20 days | ฿4,180.00 |
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| 25mg | 10-20 days | ฿8,010.00 |
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4-Amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
Used in pharmaceutical research as a potent and selective inhibitor of anaplastic lymphoma kinase (ALK). It shows promising activity against ALK-driven cancers, particularly non-small cell lung cancer (NSCLC) with ALK gene rearrangements. The compound effectively crosses the blood-brain barrier, making it valuable in treating brain metastases associated with ALK-positive tumors. Its high selectivity reduces off-target effects, improving therapeutic efficacy and patient tolerance in clinical settings.
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| Stable in pH range | - |
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