NU7026
2mM in DMSO
- Product Code: 216417
CAS:
154447-35-5
| Molecular Weight: | 281.31 g./mol | Molecular Formula: | C₁₇H₁₅NO₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD06798345 | |
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| Density: | Storage Condition: | -20°C |
Product Description:
NU7026 is widely used in cancer research due to its ability to inhibit DNA-dependent protein kinase (DNA-PK), a key enzyme involved in the repair of DNA double-strand breaks. By blocking this repair pathway, NU7026 enhances the effectiveness of DNA-damaging agents such as ionizing radiation and certain chemotherapeutic drugs. It is commonly employed in studies aiming to overcome tumor resistance to radiotherapy and chemotherapy, particularly in cancers where DNA repair mechanisms contribute to treatment failure. Its application is primarily confined to preclinical research, where it serves as a tool compound to probe DNA repair pathways and to develop combination therapies that increase cancer cell sensitivity to genotoxic treatments.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿3,690.00 |
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NU7026
NU7026 is widely used in cancer research due to its ability to inhibit DNA-dependent protein kinase (DNA-PK), a key enzyme involved in the repair of DNA double-strand breaks. By blocking this repair pathway, NU7026 enhances the effectiveness of DNA-damaging agents such as ionizing radiation and certain chemotherapeutic drugs. It is commonly employed in studies aiming to overcome tumor resistance to radiotherapy and chemotherapy, particularly in cancers where DNA repair mechanisms contribute to treatment failure. Its application is primarily confined to preclinical research, where it serves as a tool compound to probe DNA repair pathways and to develop combination therapies that increase cancer cell sensitivity to genotoxic treatments.
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