N-(tert-butyldimethylsilyloxy)-4-methylbenzenesulfonamide
≥95%
- Product Code: 216937
CAS:
1028432-04-3
| Molecular Weight: | 301.48 g./mol | Molecular Formula: | C₁₃H₂₃NO₃SSi |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD11976059 | |
| Melting Point: | 90-96°C | Boiling Point: | |
| Density: | 1.072±0.06 g/cm3(Predicted) | Storage Condition: | Room temperature |
Product Description:
Used as a protected hydroxylamine derivative in organic synthesis, particularly in the preparation of N-protected hydroxylamines for use in nitrene transfer reactions. It serves as a convenient reagent for the introduction of the N–OH functionality in a controlled manner, allowing for subsequent transformations such as C–H amination or aziridination when activated by appropriate metal catalysts. Its stability and selective deprotection characteristics make it valuable in multi-step syntheses, especially in pharmaceutical and agrochemical research where nitrogen-containing heterocycles are common. The tert-butyldimethylsilyl (TBS) group provides steric protection, enhancing the reagent’s shelf life and functional group compatibility.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿820.00 |
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| 1g | 10-20 days | ฿2,680.00 |
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N-(tert-butyldimethylsilyloxy)-4-methylbenzenesulfonamide
Used as a protected hydroxylamine derivative in organic synthesis, particularly in the preparation of N-protected hydroxylamines for use in nitrene transfer reactions. It serves as a convenient reagent for the introduction of the N–OH functionality in a controlled manner, allowing for subsequent transformations such as C–H amination or aziridination when activated by appropriate metal catalysts. Its stability and selective deprotection characteristics make it valuable in multi-step syntheses, especially in pharmaceutical and agrochemical research where nitrogen-containing heterocycles are common. The tert-butyldimethylsilyl (TBS) group provides steric protection, enhancing the reagent’s shelf life and functional group compatibility.
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