N-(tert-Butoxycarbonyl)-D-proline Succinimidyl Ester
98%
- Product Code: 217134
CAS:
102185-34-2
| Molecular Weight: | 312.32 g./mol | Molecular Formula: | C₁₄H₂₀N₂O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00069687 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8°C, sealed |
Product Description:
Widely used in peptide synthesis and bioconjugation, this compound enables efficient and selective coupling of D-proline to primary amines under mild conditions. Its N-hydroxysuccinimide (NHS) ester group reacts readily with amino groups in proteins, peptides, or other amine-containing molecules, making it valuable for labeling, crosslinking, and modifying biomolecules. The tert-butoxycarbonyl (Boc) protecting group ensures the amine remains blocked during reactions, preventing unwanted side reactions and improving coupling specificity. It is particularly useful in solid-phase peptide synthesis and the preparation of peptide libraries where stereochemical control is important. Due to the D-proline moiety, it can be employed to introduce conformational constraints or enhance metabolic stability in peptide-based drug design.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿990.00 |
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| 5g | 10-20 days | ฿1,710.00 |
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| 25g | 10-20 days | ฿6,120.00 |
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N-(tert-Butoxycarbonyl)-D-proline Succinimidyl Ester
Widely used in peptide synthesis and bioconjugation, this compound enables efficient and selective coupling of D-proline to primary amines under mild conditions. Its N-hydroxysuccinimide (NHS) ester group reacts readily with amino groups in proteins, peptides, or other amine-containing molecules, making it valuable for labeling, crosslinking, and modifying biomolecules. The tert-butoxycarbonyl (Boc) protecting group ensures the amine remains blocked during reactions, preventing unwanted side reactions and improving coupling specificity. It is particularly useful in solid-phase peptide synthesis and the preparation of peptide libraries where stereochemical control is important. Due to the D-proline moiety, it can be employed to introduce conformational constraints or enhance metabolic stability in peptide-based drug design.
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