3-(4-Nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
99%
- Product Code: 217430
CAS:
827026-45-9
| Molecular Weight: | 289.25 g./mol | Molecular Formula: | C₁₃H₁₁N₃O₅ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, facilitating the degradation of disease-related proteins. This makes it valuable in developing treatments for cancers such as multiple myeloma and other hematologic malignancies. Also explored in the design of PROTACs (proteolysis-targeting chimeras) for enhanced specificity and potency in drug development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 500mg | 10-20 days | $30.33 |
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| 1g | 10-20 days | $38.31 |
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| 5g | 10-20 days | $154.04 |
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| 25g | 10-20 days | $702.36 |
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| 100g | 10-20 days | $2,234.79 |
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3-(4-Nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, facilitating the degradation of disease-related proteins. This makes it valuable in developing treatments for cancers such as multiple myeloma and other hematologic malignancies. Also explored in the design of PROTACs (proteolysis-targeting chimeras) for enhanced specificity and potency in drug development.
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