N-(3-(5-Mercapto-1H-tetrazol-1-yl)phenyl)acetamide
98%
- Product Code: 217455
CAS:
14070-48-5
| Molecular Weight: | 235.27 g./mol | Molecular Formula: | C₉H₉N₅OS |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00603728 | |
| Melting Point: | 185-187°C | Boiling Point: | |
| Density: | 1.51g/mL | Storage Condition: | Room temperature, dry |
Product Description:
Used as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. The thiol group allows for further chemical modifications, making it valuable in medicinal chemistry for creating derivatives with improved pharmacokinetic properties. Also employed in research for developing new cardiovascular medications and in the preparation of radiolabeled compounds for drug metabolism studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿830.00 |
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| 5g | 10-20 days | ฿3,700.00 |
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N-(3-(5-Mercapto-1H-tetrazol-1-yl)phenyl)acetamide
Used as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. The thiol group allows for further chemical modifications, making it valuable in medicinal chemistry for creating derivatives with improved pharmacokinetic properties. Also employed in research for developing new cardiovascular medications and in the preparation of radiolabeled compounds for drug metabolism studies.
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